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Nettet5. nov. 2024 · Scaffolds are bulk bioactive materials with specific porosity and structure to contribute to the formation new tissues for completing the medical task. In 2009, first artificial tissue was implanted successfully into a patient who suffered from the tracheoesophageal defect [ 4 ]. NettetTo fulfill these biomimetic requirements a synthetic bone scaffold must: 1. provide temporary mechanic support for affected area, 2. act as substrate for deposition of osteoids, 3. have architecture which allows flowing pr ocesses of vascularization and in-growth of bone, 4. promote migration of bone cells in a scaffold, 5. rock creek c j pettit

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