WebSpecific-pathogen-free (SPF) is a term used for laboratory animals that are guaranteed free of particular pathogens. Use of SPF animals ensures that specified diseases do not … Germ-free organisms are multi-cellular organisms that have no microorganisms living in or on them. Such organisms are raised using various methods to control their exposure to viral, bacterial or parasitic agents. When known microbiota are introduced to a germ-free organism, it usually is referred to as a gnotobiotic organism, however technically speaking, germ-free organisms are also gnotobiotic because the status of their microbial community is known. Due to lacking a microbiome, …
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WebSep 25, 2008 · Here, we describe that in IL-10 −/− mouse model of colitis induced by colonization of germ-free mice with specific pathogen-free microbiota, dietary curcumin has mild effects on mucosal damage, ... Values represent mean concentrations ± SE expressed pg/ml per 0.05 g of tissue. Duplicate measurements were performed with tissues … WebJan 16, 2007 · GF mice are protected against diet-induced obesity. ( A) Adult male C57BL/6J mice were conventionalized 3 weeks before they were switched to a high-fat Western diet. Initial weight was recorded (25.5 ± 0.4 and 26.6 ± 0.7 g for GF and conventionalized mice, respectively). shoreline oldies kincardine
What is a specific pathogen free mouse? - Studybuff
WebApr 10, 2024 · The cecum and colonic tissue microbiota and metabolite changes after rice bran consumption were previously documented in conventional and germ-free mice . The prior AOM/DSS-induced CRC study in conventional mice showed rice bran’s protective anti-cancer effect against inflammation ( Table S1 ) [ 17 ], which was indicated by smaller … WebSep 10, 2024 · A significant source of research advancement has come through the development of germ-free (GF) mice, which lack all microorganisms, effectively allowing … WebAug 1, 2024 · Fecal communities in mice that received systemic antibiotics, with or without purgative, following gavage with the same preparation of donor material used for germ-free mice, had similar Shannon indices to donor communities (mean 3.63 to 3.96 for mice and 4.29 ± 0.03 for donor, Tukey’s post hoc P > 0.05) by T 21 and T 14, respectively. shoreline online